睡眠與健康
瞓唔著關腸道健康事?
近來疫情嚴重,可能令你心緒不寧,寢食難安。長期睡眠失調不但會影響工作和學習,干擾情緒,降低生活素質,而且失眠背後可能是焦慮和抑鬱等精神疾病的反映,延誤處理可能後果堪虞。
睡眠與健康
近來疫情嚴重,可能令你心緒不寧,寢食難安。長期睡眠失調不但會影響工作和學習,干擾情緒,降低生活素質,而且失眠背後可能是焦慮和抑鬱等精神疾病的反映,延誤處理可能後果堪虞。
睡眠與健康
近來疫情嚴重,可能令你心緒不寧,寢食難安。長期睡眠失調不但會影響工作和學習,干擾情緒,降低生活素質,而且失眠背後可能是焦慮和抑鬱等精神疾病的反映,延誤處理可能後果堪虞。
我們的腸道不僅是消化管道,腸道內的大量微生物會產生多種信息分子,時刻跟神經系統溝通,並影響情緒、記憶、認知能力等精神活動。
當我們遇到持續的精神壓力時,腸壁的緊密程度會變差,造成腸漏,腸道內有害的物質會穿過腸壁,觸發免疫系統產生發炎信息回饋至大腦,並加劇焦慮和抑鬱等壓力反應。
如果我們的腸道微生態失衡,同樣會產生類似的壓力反應,加劇腸漏,引致惡性循環。因此如果腸道微生態得以改善,便可以減輕壓力帶來的影響。
1
瑞士乳桿菌(Lactobacillus helveticus)和長雙岐桿菌(Bifidobacterium longum)
2
乾酪乳桿菌(Lactobacillus casei)、嗜酸乳桿菌(Lactobacillus acidophilus)、雙叉雙岐桿菌(Bifidobacterium bifidum)和植物乳桿菌(Lactobacillus plantarum)
參考文獻
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Chao L, Liu C, Sutthawongwadee S, et al. (2020). Effects of probiotics on depressive or anxiety variables in healthy participants under stress conditions or with a depressive or anxiety diagnosis: a meta-analysis of randomized controlled trials. Front Neurol 11: 421. https://doi.org/10.3389/fneur.2020.00421
Foster JA and McVey Neufeld KA. (2013). Gut-brain axis: how the microbiome influences anxiety and depression. Trends Neurosci 36 (5): 305-312. https://doi.org/10.1016/j.tins.2013.01.005
Huang TT, Lai JB, Du YL, et al. (2019). Current understanding of gut microbiota in mood disorders: an update of human studies. Front Genet 10: 98. https://doi.org/10.3389/fgene.2019.00098
Messaoudi M, Violle N, Bisson JF, et al. (2011). Beneficial psychological effects of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in healthy human volunteers. Gut Microbes 2 (4): 256-261. https://doi.org/10.4161/gmic.2.4.16108
Rudzki L, Ostrowska L, Pawlak D, et al. (2019). Probiotic Lactobacillus plantarum 299v decreases kynurenine concentration and improves cognitive functions in patients with major depression: a double-blind, randomized, placebo controlled study. Psychoneuroendocrinology 100: 213-222. https://doi.org/10.1016/j.psyneuen.2018.10.010
Wallace CJK and Milev R. (2017). The effects of probiotics on depressive symptoms in humans: a systematic review. Ann Gen Psychiatry 16: 14. https://doi.org/10.1186/s12991-017-0138-2
Wallace CJK, Foster JA, Soares JN, et al. (2020). The effects of probiotics on symptoms of depression: protocol for a double-blind randomized placebo-controlled trial. Neuropsychobiology 79: 108-116. https://doi.org/10.1159/000496406
Wallace CJK and Milev RV. (2021). The efficacy, safety, and tolerability of probiotics on depression: clinical results from an open-label pilot study. Front Psychiatry 12: 618279. https://doi.org/10.3389/fpsyt.2021.618279