The coronavirus has affected the globe and led to a serious pandemic. The public response to the epidemic and wearing face masks every day has become the norm. As of early December 2020, there are more than 63 million confirmed cases worldwide. The death toll exceeds 1.47 million, making it incredibly contagious. With the onset of winter, the chances of upper respiratory tract infections increase, which are the symptoms of the new virus, causing panic. Many studies have illustrated that probiotics have the effect of fighting viral and bacterial infections and have the function of alleviating symptoms. Studies have indicated that taking probiotics can reduce the chance of symptoms and shorten the duration of symptoms. There are microorganisms in different parts of the human body, including the respiratory tract and lungs. The largest group is the gut microbiome. Moreover, the intestinal group communicates with the lung group, and the immune cells and small molecules exchange information and form the gut-lung axis. If the respiratory tract is infected and the pulmonary microbiome is disturbed, it can affect the balance of the gut microbiome, causing immune system lesions, and increasing the risk of subsequent infections.
Imbalance Of the Gut Microbiome: Virus Takes Advantage of The Void
A recent study published by The Chinese University of Hong Kong found that patients infected with the novel coronavirus had significantly fewer gut microbial species than healthy people. Even after recovery, the unhealthy ratio of fewer good bacteria versus more harmful bacteria is not restored, and some bacterial species are related to the severity of the disease. The survey also found that the Bacteroidetes bacteria content in the patient’s stool has reduced. These bacteria reduced the angiotensin conversion of viruses to human cells (the angiotensin-converting enzyme receptor, ACE-2 receptor), This reduces the chance of the virus entering the human cell. when the defence mechanism is blocked, the virus takes advantage of the void.
Studies have shown that [probiotics] can enhance resistance
Probiotics are widely recognized as safe and effective health supplements, and numerous studies support probiotics to fight viral and bacterial infections and alleviate symptoms. The data come from large and credible studies which are double-blind randomized controlled trials with meta-analyses. One example is a comprehensive analysis of more than 3,700 participants in 13 double-blind randomized controlled tests that showed a 47% reduction in the incidence of symptoms and a 1.89-day reduction in the average duration of symptoms in probiotic users. The mechanism by which probiotics can regulate the immune system is to keep the tight connections between intestinal cells intact, creating a protective barrier, and probiotics can also activate immune cell manufacturing of s and a series of cytokines and interleukins to stimulate a specific CD4 and CD8 white cells, macrophages, natural killer cells, B lymphocytes and other members of the immune system fight the virus.
Many [probiotics] have their strengths and can cope with different symptoms
In an international clinical study of more than 5,000 infants and more than 100 adults, Lactobacillus plantarum is demonstrated to reduce the risk of respiratory infections and reduce the severity of infections. In another double-blind randomized controlled test using the same probiotics, the average symptom time in the group taking the probiotic preparation was reduced by 5.09 days and the frequency of infections was reduced by 0.32 folds. in a study in which more than 500 adolescents participated, it was shown that Lactobacillus gasseri, Bifidobacterium longum, and Bifidobacterium bifidum were possible to shorten the duration of flu symptoms. While in a study of more than 1600 schoolchildren, Lactobacillus brevis has been shown it has a similar effect in shortening the duration of flu symptoms. Lactobacillus casei also has the effect of reducing the frequency and severity of respiratory infections. Another probiotic Lactobacillus acidophilusplays an important role in the fight against viruses. Studies have shown that Lactobacillus acidophilus can improve the expression of the genes type 1, IL-10 and IL-12, activate the immune system, and fight viruses efficiently. It has been reported that people taking Lactobacillus reuterihave a significant increase in T cells labelled with CD4, CD25, and FoxP3 in their bodies, which helps calm the hyperactive immune system.
4 Key Points for Choosing a Probiotic
Although many studies have brought out the benefits of probiotic supplementation, not all probiotic products available on the market have the same effect. There are four conditions for choosing a suitable probiotic product: Firstly, for probiotics to maintain activity and they must block gastric acid and bile salts from reaching the intestinal tract. Therefore, to produce beneficial bacteria, it is necessary to pass the gastric acid and bile salt tolerance test, so that a sufficient dose of active probiotics reaches the end of the small and large intestine; secondly, they must pass food safety tests. Such as heavy metal testing to ensure its safety; thirdly, they contain a lot of prebiotics. Studies have shown that prebiotics has a strong proliferation effect on the probiotic flora in the intestine, and at the same time have the same effect as plant fibres, which can promote gastrointestinal motility and improve intestinal function; fourthly, in cooperation with different strands of probiotics, the corresponding effects can be achieved for different sub-health problems. There is also a scientific research institution in the Science Park, which has successfully developed PGut Premium probiotics by using the above “premium” strains: including the proprietary probiotic strains Lactobacillus plantarum GKM3, Lactobacillus gasseri, Bifidobacterium longum, Bifidobacterium bifidum etc., combined with triple prebiotics (chicory fibre, fructooligosaccharides and galactooligosaccharides) and postbiotics (HK-LP) to strengthen the colonization function of probiotics. This formula of probiotics has more precise and advanced packaging technology to encapsulate the bacteria and has been tested in extreme environments simulating the formation of gastric acid and bile salts in the human digestive tract. Through laboratory tests, the results show that probiotics can still maintain a survival rate of more than 98%, effectively fight against gastric acid and bile salts, and active bacteria can reach the intestines.
In the case of repeated epidemics, autoimmunity plays a very important role. However, any supplement also has its limitations. During this pandemic, maintain adequate sleep, stay in a cheerful mood, in cooperation with a balanced diet, appropriate exercise and choose the effective probiotics help to improve your immunity and reduce the risk of respiratory tract infections.